Applications of Prolotherapy in Chronic Musculoskeletal Pelvic Pain: A Narrative Review

Published on July 23, 2026

Curr Pain Headache Rep. 2026 Jul 23;30(1):95. doi: 10.1007/s11916-026-01530-3.

ABSTRACT

PURPOSE OF REVIEW: Though the utilization of prolotherapy has been described since the 1930s, there still exists a paucity of information about its contemporary application as an alternative or complementary treatment modality for chronic musculoskeletal pelvic pain.

RECENT FINDINGS: Prolotherapy may serve as a safe and efficacious nonsurgical intervention for the treatment of a multitude of chronic pelvic pain conditions, particularly in cases where conservative medical management and physical therapy have failed. In this narrative review, we discuss the current evidence suggesting that prolotherapy is effective in the treatment of various pain conditions involving the musculoskeletal structures of the pelvis such as sacroiliac joint pain, coccydynia, deep gluteal syndrome, and chronic groin pain. Future prospective clinical studies are necessary to better define and characterize the role of prolotherapy as a mainstay of treatment for chronic pelvic pain.

PMID:42489756 | DOI:10.1007/s11916-026-01530-3

Continue reading on website
Other news

Efficacy of percutaneous cryoneurolysis for pain management of rib fractures

July 23, 2026
Minerva Anestesiol. 2026 Jul-Aug;92(7-8):718-725. doi: 10.23736/S0375-9393.26.19686-2.ABSTRACTRib fractures are a common injury with several etiologies. Various techniques for managing pain with rib fractures have evolved over the past few decades. Pain control is key in reducing further complications of this traumatic injury. In this regard, cryoneurolysis is a form of interventional pain managem

Platelet-Rich Plasma in Chronic Joint Pain: An Autologous Alternative to Steroids

July 23, 2026
Curr Pain Headache Rep. 2026 Jul 23;30(1):94. doi: 10.1007/s11916-026-01524-1.ABSTRACTPURPOSE OF REVIEW: Chronic joint pain, most caused by osteoarthritis, is one of the leading causes of disability worldwide. When conservative management fails, interventional therapies are introduced, with corticosteroid injections being one of the most utilized. However, its clinical utility is limited by its sh