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    Highlighted News

    Results (2179)

    Newest
    Extending the evidence for Scrambler Therapy to reduce pain in chemotherapy-induced peripheral neuropathy

    Extending the evidence for Scrambler Therapy to reduce pain in chemotherapy-induced peripheral neuropathy

    Int Rev Psychiatry. 2026 Jun 5:1-10. doi: 10.1080/09540261.2026.2682198. Online ahead of print.ABSTRACTChemotherapy-induced peripheral neuropathy (CIPN) significantly burdens cancer patients, often leading to treatment interruptions. Scrambler Therapy (ST)-a noninvasive cutaneous electroanalgesia device-has emerged as a promising alternative for treating CIPN pain. This retrospective chart review
    June 5, 2026
    ACR Appropriateness Criteria  Epigastric Pain

    ACR Appropriateness Criteria Epigastric Pain

    J Am Coll Radiol. 2026 Jun 5:S1546-1440(26)00234-6. doi: 10.1016/j.jacr.2026.05.003. Online ahead of print.ABSTRACTMany different pathologies can present with epigastric pain, and the overlap of the symptoms of these varying entities can make diagnosis difficult clinically. This document focuses on scenarios including esophageal and gastroduodenal perforations, those occurring after post reflux su
    June 5, 2026
    High-Frequency Global Postoperative Status PROMs Track Pain Peaks and Analgesic Use After Degenerative Lumbar Spine Surgery

    High-Frequency Global Postoperative Status PROMs Track Pain Peaks and Analgesic Use After Degenerative Lumbar Spine Surgery

    Global Spine J. 2026 Jun 5:21925682261449153. doi: 10.1177/21925682261449153. Online ahead of print.ABSTRACTStudy Design Prospective observational cohort study.Objective Standard postoperative follow-up often fails to capture rapid fluctuations in symptoms after degenerative lumbar spine surgery. This study evaluated the construct validity of a high-frequency, low-burden "Global Postoperative Stat
    June 5, 2026
    Effects of yoga on pain, sleep quality, and aerobic endurance in young women with primary dysmenorrhea: A randomized controlled trial

    Effects of yoga on pain, sleep quality, and aerobic endurance in young women with primary dysmenorrhea: A randomized controlled trial

    Health Care Women Int. 2026 Jun 5:1-16. doi: 10.1080/07399332.2026.2682319. Online ahead of print.ABSTRACTPrimary dysmenorrhea (PD) is a prevalent condition in young women, characterized by menstrual pain, sleep disturbances, and reduced physical activity. Yoga has been suggested as a non-pharmacological intervention. We examined the effects of a 12-week yoga program on menstrual pain, sleep quali
    June 5, 2026
    The efficacy of ChatGPT as a student resource for the diagnosis and treatment of neck pain

    The efficacy of ChatGPT as a student resource for the diagnosis and treatment of neck pain

    Disabil Rehabil. 2026 Jun 5:1-11. doi: 10.1080/09638288.2026.2681561. Online ahead of print.ABSTRACTINTRODUCTION: The use of Chat Generative Pretrained Transformer (ChatGPT) is becoming a highly used source of clinical information. No study has evaluated ChatGPT's effectiveness in providing educational material to students about neck pain.METHODS: This cross-sectional study included 21 queries eva
    June 5, 2026
    Efficacy and tolerability of the pharmaconutraceutical complex Theraflex Ultra in the treatment of patients with chronic non-specific lower back pain due toprimarily discogenic pathology (FORSAGE study)

    Efficacy and tolerability of the pharmaconutraceutical complex Theraflex Ultra in the treatment of patients with chronic non-specific lower back pain due toprimarily discogenic pathology (FORSAGE study)

    Zh Nevrol Psikhiatr Im S S Korsakova. 2026;126(5):108-114. doi: 10.17116/jnevro2026126051108.ABSTRACTOBJECTIVE: To evaluate the efficacy and tolerability of the pharmaconutraceutical complex, Theraflex Ultra, based on undenatured (native) type II collagen, in the treatment of discogenic chronic low back pain (CLBP).MATERIAL AND METHODS: This open, multicenter, observational study included 50 patie
    June 5, 2026
    Clinical features of chronic pain and premorbid factors in patients with various phenotypes of metabolic syndrome

    Clinical features of chronic pain and premorbid factors in patients with various phenotypes of metabolic syndrome

    Zh Nevrol Psikhiatr Im S S Korsakova. 2026;126(5):95-100. doi: 10.17116/jnevro202612605195.ABSTRACTOBJECTIVE: To identify the clinical features associated with chronic pain and the premorbid factors in patients with metabolic syndrome of various phenotypes.MATERIALS AND METHODS: In this prospective comparative cohort study involving 118 patients with chronic pain, participants were divided into fo
    June 5, 2026
    Notice of Pre-application Webinar for the NCI Community Oncology Research Program (NCORP)

    Notice of Pre-application Webinar for the NCI Community Oncology Research Program (NCORP)

    Notice NOT-CA-26-016 from the NIH Guide for Grants and Contracts
    June 5, 2026
    Evoked temporal summation in dogs to assess pain central sensitization and modulation - A feasibility study

    Evoked temporal summation in dogs to assess pain central sensitization and modulation - A feasibility study

    PLoS One. 2026 Jun 2;21(6):e0349863. doi: 10.1371/journal.pone.0349863. eCollection 2026.ABSTRACTCentral sensitization and pain endogenous controls imbalance were reported in humans affected by chronic pain. In cats, nociplastic changes, such as the wind-up phenomenon, (i.e., decreased tolerance to repeated stimuli) were described using a validated mechanical device inducing temporal summation of
    June 5, 2026
    Nociceptor circadian clock genes control excitability and pain perception in mice in a sex- and time-dependent manner

    Nociceptor circadian clock genes control excitability and pain perception in mice in a sex- and time-dependent manner

    Nat Commun. 2026 Jun 1. doi: 10.1038/s41467-026-73772-z. Online ahead of print.ABSTRACTNociception is critical for pain perception and survival and begins with the activation of nociceptors, specialized sensory neurons located in the dorsal root ganglia (DRGs). Both sex and circadian rhythms, governed by clock genes, seem to play a significant role in modulating pain perception. However, the poten
    June 5, 2026
    Digital health and telemedicine for perioperative pain management in patients with chronic pain

    Digital health and telemedicine for perioperative pain management in patients with chronic pain

    Curr Opin Anaesthesiol. 2026 May 5. doi: 10.1097/ACO.0000000000001664. Online ahead of print.ABSTRACTPURPOSE OF REVIEW: Patients with chronic pain face elevated risks of inadequate postoperative analgesia, prolonged opioid use, and chronic postsurgical pain. Digital health technologies have expanded rapidly into perioperative care, yet their implications for chronic pain populations and for health
    June 5, 2026
    Pain perception and patient tolerance to intra-articular ozone-oxygen injections in the treatment of temporomandibular joint osteoarthritis

    Pain perception and patient tolerance to intra-articular ozone-oxygen injections in the treatment of temporomandibular joint osteoarthritis

    J Craniomaxillofac Surg. 2026 Jun 1:104577. doi: 10.1016/j.jcms.2026.104577. Online ahead of print.ABSTRACTThis study aimed to investigate pain perception and patients' tolerance to intra-articular medical ozone (IA-MO) injection for treating temporomandibular joint osteoarthritis (TMJ-OA), and to examine their associations with clinical symptoms and with CBCT and MRI findings. In 49 patients with
    June 5, 2026
    Differentiating Trigeminal Neuralgia From Persistent Idiopathic Dentoalveolar Pain and Persistent Idiopathic Facial Pain in Oral and Maxillofacial Surgery

    Differentiating Trigeminal Neuralgia From Persistent Idiopathic Dentoalveolar Pain and Persistent Idiopathic Facial Pain in Oral and Maxillofacial Surgery

    J Oral Maxillofac Surg. 2026 Jun;84(6):823-825. doi: 10.1016/j.joms.2026.01.075.ABSTRACTThe diagnostic distinction between trigeminal neuralgia (TN), persistent idiopathic dentoalveolar pain, and persistent idiopathic facial pain remains a challenge for oral and maxillofacial surgeons. While neurovascular compression is often viewed as a definitive indicator for surgical intervention, recent evide
    June 5, 2026
    A Critical Role for alpha7 Nicotinic Acetylcholine Receptor Signaling in Myeloid Lineage Cells in Chronic Neuropathic and Inflammatory Pain Responses

    A Critical Role for alpha7 Nicotinic Acetylcholine Receptor Signaling in Myeloid Lineage Cells in Chronic Neuropathic and Inflammatory Pain Responses

    J Pain. 2026 Jun 1:106339. doi: 10.1016/j.jpain.2026.106339. Online ahead of print.ABSTRACTNeuroinflammation influences the development of chronic pain, an increasingly prevalent condition impacting the lives of many worldwide. Given the challenges of managing chronic pain, it is essential to explore new neuroimmune targets for the development of safe and effective analgesics. α7 nicotinic acetylc
    June 5, 2026
    Social determinants associated with unhealthy lifestyles in adults over 60 years of age with chronic musculoskeletal pain

    Social determinants associated with unhealthy lifestyles in adults over 60 years of age with chronic musculoskeletal pain

    Rev Esp Anestesiol Reanim (Engl Ed). 2026 Jun 1:502129. doi: 10.1016/j.redare.2026.502129. Online ahead of print.ABSTRACTINTRODUCTION: Chronic musculoskeletal pain in older adults is associated with unhealthy lifestyles, possibly influenced by social determinants of health (SDH).OBJECTIVE: To identify the association between SDH and unhealthy lifestyles in older adults with chronic musculoskeletal
    June 5, 2026
    Spinal NLRP3 blockade reverses morphine-prolonged neuropathic pain and proinflammatory immune actions in prenatal alcohol-exposed male mice

    Spinal NLRP3 blockade reverses morphine-prolonged neuropathic pain and proinflammatory immune actions in prenatal alcohol-exposed male mice

    Neuropharmacology. 2026 Jun 1:111052. doi: 10.1016/j.neuropharm.2026.111052. Online ahead of print.ABSTRACTPrenatal alcohol exposure (PAE) exerts long-term alterations in the adult neuroimmune system. Previous work showed that PAE exacerbates morphine-mediated immune responses, prolonging nerve injury-induced allodynia and promoting aberrant NLRP3-driven inflammation in both the periphery and spin
    June 5, 2026
    Beyond Pain: Psychological Profiles in Chronic Migraine Compared With Fibromyalgia and Their Comorbidity

    Beyond Pain: Psychological Profiles in Chronic Migraine Compared With Fibromyalgia and Their Comorbidity

    Ann N Y Acad Sci. 2026 Jun;1560(1):e70304. doi: 10.1111/nyas.70304.ABSTRACTChronic migraine (CM) and fibromyalgia (FM) are central sensitization pain conditions, with FM representing a prototypical nociplastic disorder. While both involve altered pain processing, their psychological profiles may differ, particularly in comorbid forms. In this cross-sectional multicenter study, 318 women were asses
    June 5, 2026
    Clinical efficacy of traditional Chinese medicine Deqi acupuncture for individuals with chronic non-specific low back pain: Protocol for a randomized controlled trial

    Clinical efficacy of traditional Chinese medicine Deqi acupuncture for individuals with chronic non-specific low back pain: Protocol for a randomized controlled trial

    Acta Psychol (Amst). 2026 Jun 2;267:107161. doi: 10.1016/j.actpsy.2026.107161. Online ahead of print.ABSTRACTBACKGROUND: Chronic non-specific low back pain (CNSLBP) imposes a substantial economic burden. Acupuncture, a key modality in Chinese medicine, is widely used for CNSLBP. However, the therapeutic efficacy of acupuncture may be underestimated due to inadequate induction and evaluation of deq
    June 5, 2026
    Misalignment between subjective and objective sleep in chronic pain: The role of depressive symptoms

    Misalignment between subjective and objective sleep in chronic pain: The role of depressive symptoms

    Sleep Med. 2026 May 30;145:109050. doi: 10.1016/j.sleep.2026.109050. Online ahead of print.ABSTRACTINTRODUCTION: Poor sleep is consistently reported by chronic pain patients, while physiological sleep findings remain inconclusive. Limited evidence suggests depression may account for this discrepancy. This study investigated subjective-objective discrepancies in sleep efficiency and sleep disturban
    June 5, 2026
    Transcutaneous vagus nerve stimulation for postoperative pain reduction in patients with childhood trauma: A randomized controlled pilot study

    Transcutaneous vagus nerve stimulation for postoperative pain reduction in patients with childhood trauma: A randomized controlled pilot study

    J Psychosom Res. 2026 May 23;209:112874. doi: 10.1016/j.jpsychores.2026.112874. Online ahead of print.ABSTRACTBACKGROUND: Transcutaneous auricular vagus nerve stimulation (taVNS) is a promising non-pharmacological approach for postoperative pain management, but its interaction with childhood trauma (CT) remains unclear. This three-armed randomized controlled trial examined the analgesic efficacy o
    June 5, 2026