Notice of Informational Webinar on the NIGMS Centers of Biomedical Research Excellence: Expansion and Sustainability Phases (COBRE-E/S) Program

Published on June 25, 2026

Notice NOT-GM-26-008 from the NIH Guide for Grants and Contracts

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Self-Directed vs Clinician-Delivered Cognitive Behavioral Therapy for Chronic Pain: A Randomized Clinical Trial

June 25, 2026
JAMA. 2026 Jun 24:1-13. doi: 10.1001/jama.2026.7861. Online ahead of print.ABSTRACTIMPORTANCE: Cognitive behavioral therapy for chronic pain (CBT-CP) is a first-line nonpharmacological treatment, but uptake remains low due to multiple access barriers.OBJECTIVE: To assess the effectiveness of self-directed CBT-CP with asynchronous, personalized feedback relative to clinician-delivered CBT-CP under

Distinct neuroinflammatory effects of individual chemotherapeutics shape chemotherapy-induced peripheral neuropathy in a novel mouse model of CVAD combination regimen

June 25, 2026
Chemotherapy-induced peripheral neuropathy is a common, dose-limiting toxicity of cancer treatment for which no disease-modifying therapies exist. Vincristine-induced neuropathy has been linked to neuroimmune activation and interleukin-1 (IL-1) signaling; however, vincristine is almost exclusively administered as part of combination chemotherapy regimens, where the relevance of IL-1–dependent mech