International Pain and Spine Intervention Society emergency protocols: Allergic and anaphylactic reactions

Published on June 19, 2026

Interv Pain Med. 2026 Jun 10;5(2):100796. doi: 10.1016/j.inpm.2026.100796. eCollection 2026 Jun.

ABSTRACT

This protocol reviews the recognition and management of allergic reactions and anaphylaxis during interventional pain procedures. It describes the spectrum of hypersensitivity reactions, ranging from mild dermatologic symptoms to life-threatening multisystem anaphylaxis with airway compromise and cardiovascular collapse. Emphasis is placed on early recognition, immediate epinephrine administration, airway stabilization, intravenous fluid resuscitation, and transfer to higher-level care.

PMID:42317770 | PMC:PMC13273699 | DOI:10.1016/j.inpm.2026.100796

Continue reading on website
Other news

International Pain and Spine Intervention Society Emergency Protocols: Intra-arterial Injection

June 19, 2026
Interv Pain Med. 2026 Jun 11;5(2):100776. doi: 10.1016/j.inpm.2026.100776. eCollection 2026 Jun.ABSTRACTThis protocol discusses the risks associated with inadvertent intra-arterial injection during spine interventions, including stroke, seizure, spinal cord infarction, and paralysis. It highlights the dangers of particulate steroid embolism and arterial vasospasm, particularly during transforamina

Multisite Chronic Pain Reveals Neuro-Immune-Metabolic Dysregulation across Rheumatoid Arthritis and Depression

June 19, 2026
Research (Wash D C). 2026 Jun 17;9:1298. doi: 10.34133/research.1298. eCollection 2026.ABSTRACTMultisite chronic pain (MCP) frequently co-occurs with immune and depressive disorders, yet whether it reflects coordinated cross-domain multi-omic dysregulation remains unknown. Using UK Biobank data (19,484 baseline participants; 32,870 to 399,476 for 15.9-year follow-up), we identified MCP-related mul