Clinical study on low-level laser therapy to control postoperative pain and quality of life in patients undergoing root canal treatment

Published on May 12, 2026

Bioinformation. 2026 Feb 28;22(2):615-619. doi: 10.6026/973206300220615. eCollection 2026.

ABSTRACT

Postoperative pain affects 25-40% of Randomized Controlled Trial (RCT) patients, impairing oral health-related quality of life (OHRQoL). This double-blind RCT randomized 80 single-visit RCT patients to low-level laser therapy (LLLT) (808 nm periapical laser) or placebo postoperatively. LLLT reduced 24-hour Visual Analog Scale (VAS) pain scores (2.1±1.2 vs 4.8±1.5; p<0.001) across all timepoints. Oral Health Impact Profile-14 (OHIP-14) scores improved significantly (15.3±3.1 vs 22.7±4.5; p<0.001) with 58% less analgesic use. Immediate LLLT advances RCT recovery as safe adjunct for pain control and enhanced OHRQoL.

PMID:42109378 | PMC:PMC13150261 | DOI:10.6026/973206300220615

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