Comparing psychological distress, health-related quality of life and pain in individuals diagnosed with endometriosis and suspected to have endometriosis: A cross-sectional analysis

Published on March 30, 2026

J Psychosom Res. 2026 Mar 26;206:112647. doi: 10.1016/j.jpsychores.2026.112647. Online ahead of print.

ABSTRACT

PURPOSE: To assess whether pain, psychological distress, and health-related quality of life (HRQoL) differ in individuals diagnosed with endometriosis and those suspected to have endometriosis.

METHODS: Cross-sectional online survey of individuals with a confirmed (n = 550) or suspected (n = 103) diagnosis of endometriosis, recruited via the social media of Australian endometriosis organisations. Demographic and endometriosis-specific characteristics as well as measures of pain, psychological distress, and HRQoL were collected. Multivariate Analysis of Covariance was conducted to compare groups on key variables.

RESULTS: The suspected endometriosis group reported significantly greater pelvic pain and symptoms of anxiety than the diagnosed group.

CONCLUSIONS: When accounting for covariates, individuals suspected to have endometriosis reported significantly higher pain and anxiety symptoms than those diagnosed. This suggests that diagnosis may be associated with lower levels of pain and anxiety, possibly due to improved accessibility to treatment and removal of uncertainty.

PMID:41905339 | DOI:10.1016/j.jpsychores.2026.112647

Continue reading on website
Other news

Central Sensitization and Neuropathic Pain in Hemiplegic Shoulder Pain: A Cross-Sectional Study

March 30, 2026
Medeni Med J. 2026 Mar 27;41(1):59-68. doi: 10.4274/MMJ.galenos.2026.60497.ABSTRACTOBJECTIVE: Hemiplegic shoulder pain (HSP) is a common complication that can significantly impair motor recovery, functional independence, and quality of life in stroke survivors. Although the condition has traditionally been attributed to musculoskeletal factors, recent evidence highlights the roles of neuropathic p

Targeting the medial prefrontal cortex with transcranial temporal interference stimulation (tTIS) alleviates chronic pain

March 30, 2026
Biol Psychiatry. 2026 Mar 27:S0006-3223(26)01110-8. doi: 10.1016/j.biopsych.2026.03.995. Online ahead of print.ABSTRACTBACKGROUND: Chronic pain involves prefrontal maladaptation, but noninvasive modulation of the medial prefrontal cortex (mPFC) remains challenging. We investigated whether transcranial temporal interference stimulation (tTIS) could alleviate chronic pain and explored neural mechani