Spinal Cord Stimulation for Chronic Neuropathic Pain in Adrenomyeloneuropathy: A Case Report

Published on March 5, 2026

Pain Med Case Rep. 2026 Feb;10(1):41-46.

ABSTRACT

BACKGROUND: Neuropathic pain in adrenomyeloneuropathy (AMN) is a poorly understood phenomenon, with no consensus on treatment options. We report for the first time the successful treatment of medication-refractory neuropathic pain in AMN with thoracic spinal cord stimulation (SCS).

CASE REPORT: A 33-year-old man with AMN presented to clinic with a 10-year history of progressive bilateral distal leg pain and numbness, and a diagnosis by electromyoneurography of demyelinating polyneuropathy, refractory to best medical therapy. After a successful percutaneous trial, he underwent insertion of a paddle system spanning T10-T12. At 3 and 12 months, validated questionnaires revealed improved pain and psychosocial functioning.

CONCLUSIONS: We therefore advocate for prompt referral to pain specialists for further workup and management, including consideration of SCS.

PMID:41779991

Continue reading on website
Other news

Radiofrequency Ablation for the Treatment of Pain Related to Bertolotti's Syndrome: A Case Report

March 5, 2026
Pain Med Case Rep. 2026 Feb;10(1):17-20.ABSTRACTBACKGROUND: Bertolotti's syndrome is a congenital spinal disorder marked by back pain due to a lumbosacral transitional vertebra, often presenting with sacroiliac joint, groin, and hip pain. This condition results from the articulation of the lumbar 5 vertebra transverse processes with the sacrum, causing both radicular and pseudoradicular pain.CASE

Peripheral Nerve Stimulation for the Management of Chronic Pain Syndrome: A Case Study of Complex Regional Pain Syndrome Posttrauma and After Surgery in the Leg

March 5, 2026
Pain Med Case Rep. 2026 Feb;10(1):47-53.ABSTRACTBACKGROUND: Complex regional pain syndrome (CRPS) is a very challenging condition to treat. We present a case resistant to conservative management that was treated by peripheral nerve stimulation (PNS).CASE REPORT: Our case study highlights the efficacy of PNS in the management of chronic pain syndromes, specifically CRPS, following major trauma and